Julius Caesar said “it is easier to find men who will volunteer to die than endure pain with patience.” Dealing with pain takes more than enduring; for chronic pain, it requires strategy and persistence. Pain relief is a marathon, not a sprint, but with an understanding of the nature of pain and new tools home pain management can actually be easier than in a healthcare setting. Understanding Pain: The experience of pain is not just nerves firing and signaling the brain. Instead, pain is a complex array of causes and consequences. As an alarm system, pain notifies the brain of danger, just like an alarm system around a vulnerable basement window. With persistent threats, more and more alarms are installed in an attempt to keep the location safe. Once the cause of the danger is gone, alarms may be so sensitive that they still go off. While physical alarms can be uninstalled, dismantling the alarms from chronic pain is less straightforward but just as necessary. Chronic pain physically changes the brain itself: before knee replacement, the size of the thalamus enlarges from processing pain. Within 6 months after the bad knee (and pain) are gone, it returns to normal size.